本研究综合考虑了影响白血病患者预后的内外因素,对410 例白血病患者的24个预后因素进行了单因素和多因素Cox 模型分析,筛选出9个对白血病预后有显著影响的因素,即年龄、发热、骨髓幼稚细胞百分比、化疗与否、疗程次数、疗效、首次出院时病情、住院次数及白血病分类,由此建立白血病患者的生存数学模型,并用相应的预测模型进行预测指数分析,其灵敏度、特异度、阳性预测值、阴性预测值及可靠性均高于以往报道所用的逐步回归法建立数学模型的预后判断正确率。 In this study, the prognostic factors of leukemia were comprehensively considered. Based on the univariate and multivariate Cox model analysis of 24 prognostic factors in 410 patients with leukemia, nine factors that significantly affected the prognosis of leukemia were screened, that is, age, Fever, the percentage of immature marrow cells, the number of chemotherapy or not, the duration of treatment, the condition of first discharge, the number of hospitalizations and the classification of leukemia, Specificity, positive predictive value, negative predictive value and reliability were higher than the previously reported stepwise regression method used to establish the mathematical model of prognosis to determine the correct rate.