高血压治疗的最终目标在于预防以脑卒中、缺血性心脏病为代表的心脑血管疾病的发生。应用降压药物的治疗方法可以预防心脑血管合并症的发生,已被欧美大规模临床流行病学调查结果所证实。然而,这些调查的大部分以壮年为对象,还没有确定对高龄老人,特别是对动脉硬化引起的继发性收缩期高血压,还未证明降压药是否有效。欧洲高龄老人高血压共同研究组(EWPHE)的研究是以60岁以上的舒张期高血压患者为对象,经利尿降压药(噻嗪类、三氨苯喋啶)为基础,经过7年的观察,与安慰剂组相比,死于心脏病的患者减少了38%,差异显著。死于脑血管病者降低32%,亦有显 The ultimate goal of treatment of hypertension is to prevent the occurrence of cardiovascular and cerebrovascular diseases such as stroke and ischemic heart disease. Application of antihypertensive drug treatment can prevent cardiovascular complications, has been confirmed by large-scale clinical epidemiological survey results in Europe and the United States. However, the majority of these surveys, targeting adolescent years, have not identified the efficacy of antihypertensive drugs in elderly people, especially those with secondary systolic hypertension caused by atherosclerosis. The European Study on Elderly Hypertension (EWPHE) is based on diastolic antihypertensives (thiazides, triamterene) for diastolic hypertension over the age of 60 and after seven years Observed, compared with the placebo group, patients died of heart disease decreased by 38%, the difference was significant. Reduce 32% of those who died of cerebrovascular disease, also significant