在制备多相脂质体的注射剂时,通常采用非离子型表面活性剂如吐温类及司盘类。主要由于它们具有乳化力强,毒性低,制剂稳定性好等优点。但因其味苦,在口服制剂中,使病人不太乐意接受。为此,我们在制备多相脂质体口服液时,改选用其他表面活性剂。蔗糖脂肪酸酯(SE)为国内新开发的表面活性剂,具有无毒、无味、无嗅、无刺激性和兼具营养价值等特点、且具有较好的降低表面张力的作用。为此,我们在制备多 Non-ionic surfactants such as Tweens and Spans are commonly used in the preparation of multiphase liposomal injections. Mainly because of their strong emulsifying power, low toxicity, good preparation stability and so on. But because of its bitter taste, in oral preparations, so that patients are less willing to accept. To this end, we in the preparation of multiphase liposomal oral liquid, the alternative use of other surfactants. Sucrose fatty acid ester (SE) is a newly developed surfactant in China. It has the characteristics of non-toxic, tasteless, odorless, non-irritating and nutritious, and has a good effect of reducing the surface tension. To this end, we are preparing more