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作者研究了8例正常人和7例外源性哮喘患者前列腺素(PGF_2α)对肺机能的作用。 7例外源性哮喘患者(15～30岁)具有可逆性气道阻塞。全部患者对吸入性变应原针刺试验阳性,血液嗜酸性粒细胞计数大于500/立方毫米,在试验前停用单纯支气管扩张剂如舒喘灵和异丙基肾上腺素24小时以上。对照组8例(18～30岁),全无呼吸道疾患,也无支气管哮喘或过敏性疾病的个人史和家族史,5例有少量吸烟史。测定项目主要有第1秒用力呼气量(FEV_1),最大呼气中期流速(MMFR),肺活量(VC),气道相对传导率(SGaw)和闭合肺容量(CV),在测定上述项
The authors studied the effects of prostaglandin (PGF 2α) on lung function in 8 normal subjects and 7 exogenous asthma patients. Seven patients with extrinsic asthma (15 to 30 years old) had reversible airway obstruction. All patients had a positive acupuncture test for inhaled allergens with a blood eosinophil count greater than 500 per cubic millimeter, and bronchodilators such as salbutamol and isoproterenol were discontinued more than 24 hours prior to the trial. Control group, 8 patients (18 to 30 years old), no respiratory disease, bronchial asthma or allergic disease without personal history and family history, 5 patients had a small amount of smoking history. Measurements included FEV 1, MMFR, VC, SGaw, and closed lung volume (CV). After measuring the above items