论文部分内容阅读
据报道,胺碘酮(Amiodarone)的神经毒性发生率为3.2%～74%,以震颤、共济失调和外周神经病最常见。本文报道胺碘酮治疗 102例顽固性心律失常病例中神经并发症,侧重罕见的神经毒性。研究对象为胺碘酮治疗的室上速或室速病例本品起始量每日800～1600 mg,心律失常稳定后减至每日800 mg,6～8周后再减至每日600 mg;以后视临床反应调整剂量。治疗2～3个月后,平均维持量为每日468±138 mg。平均随访9±8个月(1～50
It has been reported that the incidence of neurotoxicity of amiodarone is 3.2% ~ 74%, the most common is tremor, ataxia and peripheral neuropathy. This article reports the amiodarone treatment of 102 cases of refractory arrhythmia neurological complications, focusing on rare neurotoxicity. Study of amiodarone for the treatment of supraventricular tachycardia or ventricular tachycardia The starting dose of 800 ~ 1600 mg daily, arrhythmia stabilized to 800 mg daily, 6 to 8 weeks and then reduced to 600 mg daily ; Later adjust the dose as clinical response. After 2 to 3 months of treatment, the average maintenance dose was 468 ± 138 mg daily. The average follow-up of 9 ± 8 months (1 ~ 50