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转化生长因子β1(TGF-β1)是具有调节细胞生长和分化功能的多肽类物质,功能多样:Ⅳ型胶原酶(明胶酶)是基质金属蛋白酶的一种,它几乎能降解细胞外基质所有成分,二者在恶性肿瘤的发生、发展过程中起重要作用,并为卵巢癌的诊治提供新的思路。
Transforming growth factor-β1 (TGF-β1) is a kind of polypeptide that has the function of regulating cell growth and differentiation. It is versatile: Type Ⅳ collagenase (gelatinase) is a type of matrix metalloproteinase that degrades almost all components of extracellular matrix , Both play an important role in the occurrence and development of malignant tumors and provide new ideas for the diagnosis and treatment of ovarian cancer.