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目的 :探讨多弹头射频治疗肝癌的临床近期疗效。方法 :对 36例肝癌患者进行射频治疗 ,通过对手术前后CT、B超检查的比较及AFP、肝功能、机体免疫力、体重和自觉症状的改变进行对比观察。结果 :36例于治疗后 7d、10例于治疗后 30d经B超及CT检查 :7d后 80 .6 %的病人肿瘤体积缩小了 30 %以上 ,30d后 10例病人肿瘤体积缩小了 40 %以上 ,与术前相比瘤体内血供消失。 83 .4%的病人自觉症状改善 ,AFP值下降者占 77.8% ,肝功能酶谱及胆红素均恢复正常 ,白蛋白平均增加 11.0g·L-1。体重增加 5 .6kg ,T淋巴细胞转化率平均增加 2 1%。IgG平均增加 2 .0g·L-1,无手术死亡。结论 :多弹头射频治疗肝癌的适应证广、安全可靠、疗效满意。
Objective: To explore the clinical short-term efficacy of multi-warhead radiofrequency ablation for liver cancer. Methods : Thirty-six patients with hepatocellular carcinoma were treated with radiofrequency therapy. The comparison of CT and B-ultrasound before and after surgery and the changes of AFP, liver function, body immunity, body weight and subjective symptoms were compared. RESULTS: Thirty-six patients were treated with B-ultrasound and CT after 30 days of treatment 7 days after treatment. After 7 days, the tumor volume was reduced by more than 30% in 80.6% of patients. After 30 days, the tumor volume was reduced by more than 40% in 10 patients. Compared with before surgery, the blood supply in the tumor disappeared. 83.4% of patients had improvement of subjective symptoms, 77.8% of them had decreased AFP value, liver function zymogram and bilirubin returned to normal, and albumin increased by an average of 11.0 g·L-1. With a weight gain of 5.6kg, the T-lymphocyte conversion rate increased by an average of 21%. The average IgG increased by 2.0 g·L-1 without operative mortality. Conclusion : The indications of multi-warhead radiofrequency ablation of liver cancer are wide, safe and reliable.