Currently,long-standing problems in traditional chemotherapy are the severe side effects.Antimicrobial peptides have received increasing attention as potent
Pain is one of the most widespread and difficult syndromes of humans[1-6].The cannabinoid system has been demonstrated to modulate the acute and chronic pai
IAPs(Inhibitor of Apoptosis Proteins)which are identified as key regulators of apoptosis,are overexpressed in cancer cells and may prevent cells from enteri
A growing body of evidence suggests that the endogenous ligand of NPSR,NPS,could promote arousal and anxiolytic-like effects[1-3].The predominant distributi
The ligation of peptide hydrazides at a Gly site carrying a removal auxiliary was found to be an efficient process.This technology was successfully used for
The antinociception of cannabinoid has generated a lot of interest in the past years[1].Hemopressin was reported as the first peptide ligand of the cannabin
The recent development of high efficiency solid phase peptide synthesis (HE-SPPS) offers improvements for the assembly of peptides due to its high purity,rapid