Peptide hydrazides are masked form of peptide thioesters which can be activated efficiently and ligated with Cys-peptides[1].However,peptide hydrazides were
Neuropeptide FF(NPFF)is known to be an endogenous opioid-modulating peptide and mediate a variety of biological actions[1-2].To date,the abilities of NPFF a
Currently,long-standing problems in traditional chemotherapy are the severe side effects.Antimicrobial peptides have received increasing attention as potent
Pain is one of the most widespread and difficult syndromes of humans[1-6].The cannabinoid system has been demonstrated to modulate the acute and chronic pai
IAPs(Inhibitor of Apoptosis Proteins)which are identified as key regulators of apoptosis,are overexpressed in cancer cells and may prevent cells from enteri
A growing body of evidence suggests that the endogenous ligand of NPSR,NPS,could promote arousal and anxiolytic-like effects[1-3].The predominant distributi