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目的探讨内脏脂肪素与血糖、胰岛素抵抗及冠状动脉粥样硬化之间的关系。方法将冠心病患者分为2型糖尿病冠心病组、单纯冠心病组,并以30名健康人群作为对照组,测定空腹血浆内脏脂肪素等。结果 2型糖尿病冠心病组、单纯冠心病组的血浆内脏脂肪素水平均显著高于对照组(P均<0.01)。结论血浆内脏脂肪素水平与血糖、胰岛素抵抗及冠状动脉粥样硬化相关,但不是影响冠状动脉粥样硬化的独立相关因素。
Objective To explore the relationship between visceral fat and blood sugar, insulin resistance and coronary atherosclerosis. Methods Patients with coronary heart disease were divided into two groups: type 2 diabetic coronary heart disease group and simple coronary heart disease group, and 30 healthy subjects were taken as control group to measure fasting plasma visfatin. Results The levels of plasma visfatin in type 2 diabetes mellitus and coronary heart disease were significantly higher than those in control group (all P <0.01). Conclusion Plasma visfatin levels are related to blood glucose, insulin resistance and coronary atherosclerosis, but not independent factors affecting coronary atherosclerosis.