磺胺甲基异(口恶)唑与制酸解痉药合用的情况较为常见,据报道:普鲁本辛能降低胃排空速率,而胃舒平含有颠茄浸膏可加强这一作用,结果延缓SMZ的吸收而使其疗效降低。但也有人认为这种影响并不明显。为了保证临床合理用药,我们通过动物和人体实验,对普鲁本辛、胃舒平影响SMZ 吸收情况进行了初步探讨,现将结果报告如下; Sulfamethoxazole (oxazole) and acid antispasmodic drugs used in combination is more common, it has been reported: Prostam can reduce gastric emptying rate, and stomach Shu Ping Belladonna extract can enhance this effect, the results of the delay SMZ absorption and reduce its efficacy. But some people think that this effect is not obvious. In order to ensure clinical rational use of drugs, we through the animal and human experiments, the impact of propranolol, stomach Shuping SMZ absorption conducted a preliminary study, the results are reported as follows;