瘙痒是慢性胆汁郁积性肝病的一种常见症状,但其机理仍不清楚。近年来瘙痒与胆汁酸相关学说已被否定,而某些病例应用消胆胺后瘙痒得到缓解的机理尚未阐明。作者认为在慢性胆汁郁积性肝病引起的瘙痒中组织胺可能也起了某种作用,并分别测试了原发性胆汁性 Pruritus is a common symptom of chronic cholestatic liver disease, but the mechanism remains unclear. In recent years, the theory of pruritus and bile acid has been denied, and some cases of cholestyramine has been relieved itch mechanism has not been elucidated. The authors suggest that histamine may also play a role in pruritus caused by chronic cholestatic liver disease and tested for primary biliary