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自角膜移植手术广泛开展以来,移植的免疫排斥反应是导致手术失败的主要原因。一般认为,在角膜移植免疫排斥反应中,细胞免疫起主要作用,而体液免疫仅起次要作用[1],但术后短期内发生的排斥反应是体液免疫所致[2]。我们对部分接受角膜移植手术的患者于手术前及术后的体液及细胞免疫水平进行动态观察,并将其结果作一比较,及统计学处理,以了解二者间的相关关系。
Since the widespread transplantation of corneal transplantation, graft rejection has been the main reason for the failure of surgery. It is generally accepted that cellular immunity plays a major role in corneal graft rejection and that humoral immunity plays a secondary role [1], but the rejection that occurs shortly after surgery is due to humoral immunity [2]. We conducted a dynamic observation of the humoral and cellular immunity of some patients undergoing corneal transplantation surgery before and after surgery, and compared their results with statistics to understand the correlation between the two.