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对41例正常对照组,76例胰腺疾患病人及60例非胰腺疾患病人用酶免疫法和比浊法测定血清脂肪酶及血清总淀粉酶,以评价血清免疫反应脂肪酶(IRL)诊断价值.血清IRL在13例急性胰腺炎病人中有12例升高.44例慢性胰腺炎中有12例升高,19例胰腺癌中有12例升高。血清IRL在44例慢性胰腺炎中9例降低,与晚期胰腺外分泌功能不全有关。在胰腺疾病中血清IRL的总敏感性为59％,比浊法为38％,血清淀粉酶为51％。在正常对照组与非胰腺疾病组的血清IRL特异性是80％,比浊法为86％,血清淀粉酶是88％.与
Serum lipase and serum total amylase were measured by enzyme immunoassay and turbidimetry in 41 normal controls, 76 pancreatic disease patients and 60 non-pancreatic disease patients to evaluate the diagnostic value of serum immunoreactive lipase (IRL). Serum IRL was elevated in 12 of 13 patients with acute pancreatitis, 12 of 44 with chronic pancreatitis, and 12 of 19 with pancreatic cancer. Serum IRL in 44 cases of chronic pancreatitis in 9 cases decreased, and late pancreatic exocrine insufficiency related. The overall sensitivity of serum IRL in pancreatic disease was 59%, nephelometry 38%, and serum amylase 51%. Serum IRL specificity was 80% in normal control and non-pancreatic disease groups, turbidity was 86%, and serum amylase was 88%.