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目的评价注射用天琥宁治疗急性上呼吸道感染的有效性与安全性。方法将108例急性上呼吸道感染患者随机分为A组(注射用天琥宁)、B组(注射用穿琥宁)、C组(0.9%氯化钠注射液),对三组患者的退热程度及症状积分分别进行比较。结果注射用天琥宁A组与注射用穿琥宁B组比较,在体温方面两组治疗后相比无显著统计学差异(P>0.05),但是天琥宁A组体温比穿琥宁B组降低更明显。但二者自身前后相比皆有统计学意义,二者于0.9%氯化钠注射液C组相比,在改善体温方面有显著功效(P<0.05);治疗后注射用天琥宁A组和注射用穿琥宁B组主要症状评分(发热,全身酸痛,鼻塞,咽喉疼痛,咳嗽)明显低于0.9%氯化钠注射液C组(P<0.05),三组自身相比症状评分均有降低,注射用天琥宁A组降低最明显。结论与0.9%氯化钠注射液相比较,注射用天琥宁和注射用穿琥宁,可有效消除急性上呼吸道感染的相关症状,但是注射用天琥宁的效果更明显,更能缩短病程时间,是临床治疗急性上呼吸道感染的有效治疗方法。
Objective To evaluate the efficacy and safety of dexamethasone for injection in the treatment of acute upper respiratory tract infection. Methods One hundred and eighty patients with acute upper respiratory tract infection were randomly divided into three groups: group A (dex), group B (chuanhuning injection) and group C (0.9% sodium chloride injection) And symptom scores were compared. Results There was no significant difference in body temperature between group A and group B (P> 0.05), but the group A had lower body temperature than group B . However, both of them were statistically significant before and after treatment. Both of them had significant effect on improving body temperature (P <0.05) compared with 0.9% sodium chloride injection group C; after treatment, And Chuanhuning B group were significantly lower than those in 0.9% sodium chloride injection group C (P <0.05), and the symptom scores of three groups were lower than those of 0.9% sodium chloride injection group (fever, body aches, stuffy nose, sore throat and cough) , The injection of Dexuvastatin A group to reduce the most obvious. Conclusion Compared with 0.9% sodium chloride injection, the injection of dextromethorphan and injection of chuanhuning, can effectively eliminate the symptoms of acute upper respiratory tract infection, but the effect of injection of sodium and more obvious, and can shorten the duration of the disease, Clinical treatment of acute upper respiratory tract infection is an effective treatment.