采用硝酸还原酶法和放射免疫法对43例脑梗塞患者急性期和恢复期血清NO及ET进行测定,并与正常对照组比较。结果发现,脑梗塞急性期血清NO、ET含量显著升高,NO与ET呈显著正相关;脑梗塞恢复期血清NO含量虽较对照组升高,但无统计学差异。提示NO及ET在脑缺血的发生、发展中起着同样重要的作用,在治疗脑梗塞时协调好两者的关系极为重要。 Nitric acid reductase and radioimmunoassay were used to determine serum NO and ET in 43 patients with cerebral infarction in acute phase and convalescent phase and compared with normal control group. The results showed that serum levels of NO and ET were significantly increased in the acute stage of cerebral infarction, and there was a significant positive correlation between NO and ET. Serum NO levels in the recovery stage of cerebral infarction were higher than those in the control group, but there was no significant difference. Tip NO and ET in the occurrence and development of cerebral ischemia plays an equally important role in the coordination of the treatment of cerebral infarction between the two is extremely important.