肝豆状核变性(WD)为常染色体隐性遗传性铜代谢障碍性疾病,同胞中常有数人发病,对此文献报道较多,而单卵孪生子同患本病的报道国内仅有一对。本院收治的936例WD中有4例2对单卵孪生子(0.42％)同患本病。现报告如下。 Hepatolenticular degeneration (WD) is an autosomal recessive inherited copper metabolism disorders, often siblings of several people, which is reported in the literature more, and single egg twin with the disease reported only a pair of domestic. In our hospital, 936 cases of WD, 4 cases of 2 pairs of monozygotic twins (0.42%) with the disease. The report is as follows.