论文部分内容阅读
卡特心安盐酸盐系日本1972年合成的β-受体阻滞剂,化学名为5-(3-特-丁胺-2-羟基)丙氧基-3,4-双氢化喹喏酮盐酸盐,结构式如下: 本剂为白色结晶性粉末,无臭,味苦,微溶于水,其1%水溶液的pH为5.0～6.0。本剂有较强的β-肾上腺素能阻滞作用(为心得安的20～30倍),持续时间亦长,对脏器无选择作用,具有内因性交感神经刺激作用和微弱的局麻作用(约为心得安的1/10)。作者以双盲法观察本剂对正常眼(健康成人
Carter sera hydrochloride hydrochloride Japan in 1972 synthesized β-blocker, the chemical name is 5- (3-tert-butylamine -2-hydroxy) propoxy-3,4-dihydrochloroquinolone salt Acid salt, the structural formula is as follows: The agent is white crystalline powder, odorless, bitter, slightly soluble in water, the pH of its 1% aqueous solution is 5.0 ~ 6.0. The agent has a strong β-adrenergic blockade (for the propranolol 20 to 30 times), the duration is also long, no selective effect on the organ, with internal sympathetic stimulation and weak local anesthesia (About peace of mind 1/10). The authors double-blind observation of the agent on the normal eye (healthy adults