当口服脊髓灰质炎疫苗贮存在高于冰箱温度的环境中时易于失效。在热带国家,如果冷链不好,该疫苗的失效速度更快,因而造成不良后果。Sokhey等发现口服脊髓灰质炎疫苗贮存在22℃和36℃的环境中,三周后疫苗株的感染性分别下降1.5log和3.1log。显然,有必要寻求一些能保留病毒感染性的方法。 Oral polio vaccines are prone to failure when stored in an environment above the temperature of the refrigerator. In the tropical countries, if the cold chain is not good, the vaccine will fail more quickly and cause adverse consequences. Sokhey et al. Found that oral polio vaccine was stored at 22 ° C and 36 ° C. After three weeks, the infectivity of the vaccine strain decreased by 1.5 log and 3.1 log, respectively. Obviously, there is a need to find ways to preserve the virus’s infectivity.