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1990年7月至9月我们对住院的17名急性细菌性痢疾进行培氟沙星临床治疗观察,并与诺氟沙星治疗对照比较,病例均符合1981年全军细菌性痢疾防治方案诊断标准。其中11例痢疾杆菌培养阳性并做了药敏试验。培氟沙星200mg每日二次口服,个别发热较重短期输液外,均未加用其它药物治疗。本组17例中,腹痛1天消失9例(52.9％)、2天累汁16例(94.11％)。腹泻1天复常5例(29.4％),2天累计16例(94.11％)例。便常规复常1天者11例(64.7％),2天累计16例(94.1％)。体温37℃～37.9℃8例,38℃～38.9℃6例,39℃以上3例,1天内退热16
From July to September 1990, we observed the clinical treatment of pefloxacin in 17 acute bacillary dysentery hospitalized and compared with the norfloxacin-treated control. All of the cases were in line with the diagnostic criteria of the general bacillary dysentery control program in 1981 . 11 cases of Shigella flexneri culture positive and made drug sensitivity test. Pefloxacin 200mg twice daily oral administration, individual fever heavier short-term infusion, did not add other drug treatment. The group of 17 cases, one day disappeared abdominal pain in 9 cases (52.9%), 2 days tired juice in 16 cases (94.11%). Diarrhea 1 day normalization in 5 cases (29.4%), 2 days, a total of 16 cases (94.11%) cases. Routine normal one day in 11 cases (64.7%), 2 days a total of 16 cases (94.1%). Body temperature 37 ℃ ~ 37.9 ℃ in 8 cases, 38 ℃ ~ 38.9 ℃ in 6 cases, 39 ℃ in 3 cases, 1 day antipyretic 16