“Magic” of our gastric cancer results on perioperative chemotherapy

来源 :World Journal of Gastrointestinal Pathophysiology | 被引量 : 0次 | 上传用户:dbscy001
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
AIM: To determine reproducibility of perioperative chemotherapy for gastric cancer(GC) on our settings by identifying patient’s overall survival and comparing them to larger studies.METHODS: Retrospective analysis of our series,where we present our eleven-year’s experience on GC managed according to perioperative approach of three preoperative chemotherapy cycles followed by surgery and finally three postoperative chemotherapy cycles.Chemotherapic scheme used was Xelox(Oxaliplatin and Capecitabine).Epidemiologic parameters as well as surgical variables were analysed,presented,and compared to other series with similar approaches.Survival was estimated by Kaplan Meier/log rank method and also compared to these studies.RESULTS: Mean age was 65 years old.Overall survival in our series was 37.7%,similar to other groups using perioperative schemes.Mortality was 4% and morbidity 30%,which are also similar to those groups.Survival curves were compared to larger studies,finding similarities on them.Subgroup survival analysis between chemotherapy responders and non-responders didn’t reach statically significant differences.CONCLUSION: Perioperative chemotherapic scheme can be reproduced on our setting with good results and without increasing morbidity or mortality. AIM: To determine reproducibility of perioperative chemotherapy for gastric cancer (GC) on our settings by identifying patient’s overall survival and comparing them to larger studies. METHODS: Retrospective analysis of our series, where we present our eleven-year’s experience on GC managed according to perioperative approach of three preoperative chemotherapy cycles followed by surgery and finally three postoperative chemotherapy cycles. Chemotherapic scheme used was Xelox (Oxaliplatin and Capecitabine). Epidemiologic parameters as well as surgical variables were analyzed, presented, and compared to other series with similar approaches. were estimated by Kaplan Meier / log rank method and also compared to these studies. RESULTS: Mean age was 65 years old. Overall survival in our series was 37.7%, similar to other groups using perioperative schemes. MORTURE was 4% and morbidity 30% , which are also similar to those groups. Survival curves were compared to larger studies, finding similarities on These.Subgroup survival analysis between chemotherapy responders and non-responders did not reach statically significant differences. CONCLUSION: Perioperative chemotherapic schemes can be reproduced on our settings with good results and without increasing morbidity or mortality.
其他文献
摘 要:21世纪是科学教育的时代,我国教育改革的长期指导理念是培养学生的科学素养。通过物理的学习可以帮助学生明白生活中的一些现象原理、发现活动规律,物理是一门以实验为基础进行科学研究的学科。本文主要以实验教学创新为切入点,围绕课堂物理实验教学中营造自主探究为中心,简要论述如何促进初中物理实验教学创新。  关键词:物理实验教学;创新;策略  一、 创新教育改革  创新既是进步的灵魂也是发展的动力来源
目的:过度训练可引起急性肾脏损伤,但其发病机制尚未完全明了。最近的研究认为细胞凋亡是过度训练致急性肾脏损伤的主要发病机制,然而,过度训练致肾组织细胞凋亡的分子机制尚
90年代中期以来,聚合物直接甲醇膜燃料电池(DMFC)研究取得了重要进展,其商业前景日趋明朗,正受到越来越多的关注.本文综述了DMFC膜电极制备工艺和电极结构优化的研究进展,分
目的探讨中、晚期宫颈鳞癌在进行放化疗治疗后复发未控的相关影响因素,以提高放化疗的治疗效果。方法将收治的170例中、晚期宫颈鳞癌患者的病历资料进行回顾性分析,其中未控
自 进入90年代以来,Internet的发 展汹涌澎湃,目前北美Internet骨干网上的IP业务量每6-9个月左右就翻一番,比著名的CPU性能进展的摩尔定律(约18个月左右就翻一番)还要快2-3倍。同样,中国Internet的发展也是每6个月左右增长一
Hepatocellular carcinoma(HCC) is one of the deadliest cancers in the world and is associated with a high risk of recurrence. The development of a wide range of
摘 要:在农村初中化学的教学中,影响学生化学计算能力的因素很多:如学生基础知识不牢、思维惰性、缺乏独立性等,基于这些问题,初中化学教师在教学中,应当通过夯实学生基础知识、培养学生解题技巧、拓展学生解题思路等多方入手,为促进学生化学计算能力的提升奠定基础。  关键词:初中化学;计算能力;影响因素;解决对策  化学计算是初中化学教学的重要组成部分,同时也是中考的重要内容之一。在初中化学的教学中,对学生
投影机技术和投影机市场近几年正飞速地发展,人们对投影机的观念也正在不断更新。以前,人们心目中的投影机是那种长着三只大眼睛,笨重的CRT投影机(俗称三枪投影机)。目前它所占市场份
新课标的实施改变了以往教师教、学生学的教学模式,逐渐注重把学生放在课堂主体位置上,开始尊重学生的学习个性,想办法让学生积极、主动地参与到课堂教学中,以促进学生的全面
摘 要:在初中物理教学中,学生的核心素养主要体现在科学知识、科学方法、科学态度和价值观、科学应用等方面。这就要求教师在物理教学中,应当结合学生的核心素养,转变教学思路,创新教学方法,全面提升学生的关键技能,促进学生综合素质的提升。  关键词:初中物理;核心素养;教学对策  一、 引言  有教育学家曾经说过:在学生学习的过程中,别人所传授的知识可能会被忘记,但通过自己摸索和思考得出的知识,则会永久地