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目的分析青年女性子宫内膜癌的临床、病理、治疗及预后的特点。方法对我院从2002年12月-2010年12月收治的17例小于40岁的子宫内膜癌患者的临床资料与同期大于40岁的患者进行比较分析。结果小于40岁的子宫内膜癌患者占同期子宫内膜癌患者的5.78%(17/294),随年龄增加,发病率有增加趋势。近半数患者合并有不孕不育、月经失调、内膜增生、多囊卵巢。治疗以手术为主,随访15例仍健在,5例复发,2例死亡。结论小于40岁青年女性子宫内膜癌多合并月经不调、不孕不育、内膜增生、多囊卵巢,表明其发病与雌激素有关。预后与高危因素有关,高危因素少,预后好。小于40岁青年女性子宫内膜癌患者可考虑保留生育功能或卵巢。
Objective To analyze the clinical, pathological, therapeutic and prognostic characteristics of young women with endometrial cancer. Methods The clinical data of 17 patients with endometrial carcinoma less than 40 years old who were treated in our hospital from December 2002 to December 2010 were compared with those over 40 years old in the same period. Results The endometrial cancer patients younger than 40 years accounted for 5.78% (17/294) of patients with endometrial cancer in the same period. With the increase of age, the incidence rate of endometrial cancer tended to increase. Nearly half of patients with infertility, menstrual disorders, endometrial hyperplasia, polycystic ovary. Surgical treatment was the mainstay, 15 cases were still alive, 5 cases relapsed and 2 died. Conclusion The younger women younger than 40 years of age with endometrial cancer combined with irregular menstruation, infertility, intimal hyperplasia, polycystic ovary, indicating that the incidence of estrogen-related. Prognosis and risk factors, high risk factors, good prognosis. Young women younger than 40 years of age endometrial cancer patients may consider retaining reproductive function or ovarian.