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答:X综合征是指原因不明的发作性心肌缺血,表现为典型劳力型心绞痛,而冠状动脉造影显示冠状动脉正常的一组综合征。本病多见于中年妇女。心绞痛的发作多发生在白天。发病诱因多与运动及轻微体力活动有关,95%患者的心绞痛发作前心率均有不同程度加快,血压升高。在心绞痛发作中常伴有植物神经功能紊乱症状。心电图运动试验阳性。冠状血管造影显示冠状动脉正常。~(201)铊心肌显像有异常灌注区,并且出现局部室壁运动异常和射血分数异常。诊断需除外主动脉瓣病变、肺动脉瓣狭窄、心肌病和贫血引起的心绞痛症状。 Ophark等对该类患者行左心室心肌活检研究发现,在光镜下心肌及小血管系统无明显病理改变。
Answer: Syndrome X is an episode of acute myocardial ischemia of unknown cause, manifested as typical exertional angina, and coronary angiography shows a normal set of syndromes of the coronary arteries. The disease more common in middle-aged women. The onset of angina occurs more often during the day. More incentives and exercise and mild physical activity, 95% of patients before angina pectoris heart rate has increased to varying degrees, high blood pressure. In angina attacks often accompanied by autonomic dysfunction symptoms. ECG exercise test positive. Coronary angiography showed normal coronary arteries. ~ (201) thallium myocardial imaging has abnormal perfusion area, and the emergence of regional wall motion abnormalities and ejection fraction abnormalities. Diagnostic exclusion of aortic valve disease, pulmonary stenosis, cardiomyopathy and anemia caused by angina symptoms. Ophark and other patients with left ventricular myocardial biopsy study found no significant pathological changes in the myocardium and small vessel system under light microscopy.