胡蔓藤(Gelsemium elegans Banth)属马钱科胡蔓藤属植物。药用其根、叶或全草,多鲜用,有剧毒,能祛风止痛,消肿拔毒,杀虫止痒。我们从胡蔓藤根的生物碱提取物中,通过碱性氧化铝柱、碱性硅胶干柱层析以及离心薄层层析得到七种生物碱,其中koumine、gelsemine和gelsevirine为已知碱。另外4个为新的生物碱,分别命名为胡蔓 Gelsemium elegans Banth is a genus of Manchuria. Medicinal use of its roots, leaves or whole grass, fresh use, there are highly toxic, can Qufeng pain, swelling and detoxification, insecticidal itching. We obtained seven alkaloids from alkaloid extracts from the roots of Morinda citrifolia through basic alumina columns, basic silica gel dry column chromatography, and centrifugal thin layer chromatography, among which koumine, gelsemine, and gelsevirine are known bases. The other four are new alkaloids, named Hu Man.