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为了对比研究压宁定和硝普钠在嗜铬细胞瘤围术期中行控制性降压对血流动力学的影响．选择20例ASAⅡ～Ⅲ级，不合并心肝脑肺疾病的嗜铬细胞瘤患者随机分成压宁定组和硝普钠组，每组各10例，分别静注、静滴压宁定和硝普钠，于用药前，用药后1、5、10分钟以及肿瘤切除时、肿瘤切除完毕时测定每组病人的血流动力学指标。结果表明：压宁定与硝普钠均能有效地降低血压，前者作用较迅速、平稳、安全且不加快心率，能够降低心肌耗氧，有效地预防术中心肌供血不足的发生。
In order to compare the effects of controlled intravenous nitroxide and hemostatin during perioperative period of pheochromocytoma. Twenty patients with ASA grades II～III who were not complicated with heart, liver, brain and lung diseases were randomly divided into two groups: ginsulidine group and sodium nitroprusside group, 10 in each group, respectively, intravenous injection, intravenous infusion, Ningding and nitroprusside. Before the administration of sodium, the hemodynamic parameters of each group of patients were measured at 1, 5, and 10 minutes after the administration, and at the time of tumor resection and tumor resection. The results showed that buprenorphine and sodium nitroprusside can effectively reduce blood pressure, the former is more rapid, stable, safe and does not accelerate heart rate, can reduce myocardial oxygen consumption, and effectively prevent intraoperative myocardial insufficiency.