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冠状动脉粥样硬化的高发病率和严重转归,使之急需对肯定或疑似缺血性心脏病人的冠状循环有一全面的估价。此外,局部心肌灌注的测定,对缺血性心脏病内科与外科治疗的评价极为重要。冠状动脉造影可以提供冠状动脉狭窄部位及其狭窄程度的解剖情况,但无法提供微血管水平局部心肌血流的功能情况,后者可通过放射性核素和闪烁照相机取得。再则,这一方法是非侵入性和安全的。用于测定局部心肌灌注的放射性核素示踪剂有钾类似物、颗粒示踪剂和弥散性隋性气体(~(188)氙)。后两种示踪剂需要作心脏插管。本文主要讨论钾类似物,并着重于铊-
The high incidence and serious prognosis of coronary atherosclerosis makes it an urgent need for a comprehensive assessment of the coronary circulation in patients with affirmative or suspected ischemic heart disease. In addition, the determination of local myocardial perfusion, the evaluation of medical and surgical treatment of ischemic heart disease is extremely important. Coronary angiography provides an anatomical picture of the location of the stenosed coronary artery and its stenosis but does not provide the functional status of the local myocardial blood flow at the level of the microvessels, which can be obtained with radionuclides and scintigraphy cameras. Again, this approach is non-invasive and secure. Radionuclide tracer used to determine local myocardial perfusion included potassium analogs, particle tracer and diffusive inert gas (~ (188) xenon). The latter two tracer need for cardiac catheterization. This article focuses on potassium analogues, and focuses on thallium -