作者对118例弥漫性血管内凝血患者的病因和实验室指标进行了分析,最常见的病因中全身感染39.8%,创伤16.9%,恶性病6.8%,手术68%。临床表现:出血64.4%,肾功能不良24.6%,肝功能不良18.6%,呼吸功能不良16.1%,休克14.4%,血栓栓塞现象6.8%,以及涉及中枢神经系统1.7%。26例无症状。死亡率为54.7%。年老者死亡率高,临床症状多;实验结果异常者死亡率高。除创伤死亡率较低(30%)外,其他原因对死亡率无影响。在临床症状方面,全身感染者以肝肾功能不良最为常见,而创伤者以呼吸功能不良为最常见。作者认为这一差异说明临床症状不仅受血管内凝血的影响,而且受原发病的影响。作者进行的有关凝血试验有凝血酶原时间、部份凝血活酶时间、血小板计数、凝血酶时间、纤维蛋白原定量、纤维蛋白溶解活性测定、纤维蛋白分解产物测定和鱼精蛋白试验等。结果表明,其中凝 The authors analyzed the etiology and laboratory parameters of 118 patients with diffuse intravascular coagulation. The most common causes were systemic infection 39.8%, trauma 16.9%, malignancy 6.8%, and surgery 68%. Clinical manifestations: bleeding 64.4%, renal dysfunction 24.6%, liver dysfunction 18.6%, respiratory dysfunction 16.1%, shock 14.4%, thromboembolism 6.8%, and the involvement of the central nervous system 1.7%. 26 cases asymptomatic. The death rate was 54.7%. Elderly mortality rate, clinical symptoms and more; experimental results were abnormal high mortality. Except for the low rate of trauma (30%), other causes have no effect on mortality. In clinical symptoms, systemic infection is the most common liver and kidney dysfunction, and trauma to respiratory dysfunction as the most common. The author believes that this difference shows that clinical symptoms are not only affected by intravascular coagulation, but also by the impact of the original disease. Prothrombin time, partial thromboplastin time, platelet count, thrombin time, fibrinogen quantitation, fibrinolytic activity assay, fibrinolytic product determination, and protamine assay, etc., were examined by the authors regarding coagulation tests. The results show that the coagulation