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腺样体和腭扁桃体是上呼吸道淋巴环的主要成分,能产生和分泌Ig,有免疫防御作用。但历来对二者中含Ig细胞的分布存有争论,有关ISC在二者中存在的资料更少。为此对比观察了二者中含ISC数量的差异及腺样体中ISC与年龄及疾病的关系。所检查的44个腺样体及52个扁桃体取自为扁桃体肥大或反复炎症发作的71例1～21岁患者,其中25例同时切除了扁桃体和腺样体,术毕30分钟内将标本组织制成单核细胞(MNC)悬液,用改良的酶联免疫斑点法(ELISPOT)检测ISC量。结果,在MNC悬
Adenoid and palatine tonsil is the main component of the upper respiratory tract, can produce and secrete Ig, immune defenses. However, there has always been controversy over the distribution of Ig cells in both, with less information on ISC in both. For this reason, we compared the difference of ISC content between the two and the relationship between ISC and age and disease in adenoids. Twenty-four adenoids and 52 tonsils were examined from 71 patients 1 to 21 years of age with tonsil hypertrophy or recurrent inflammatory episodes. Twenty-five of the adenoids and tonsils were resected at the same time. Tissues The mononuclear cells (MNC) suspension were prepared and the ISC content was detected by ELISPOT. The result, hanging over the MNC