克兰菲特氏综合征(Klinefelter’s Syndrome)是引起男性性腺功能低下的常见病因之一,是由于出现超数X染色体造成男子女性型乳房,睾丸萎缩而精子缺乏,但无间质细胞(Leydig细胞)的萎缩,FSH分泌增加。我院所见1例为47,xxy/46,xx。仅占各核型的3.1％,经治疗有效,现报告如下。 患者,男性,17岁。因双侧乳房增大4年,于 Klinefelter’s Syndrome is one of the most common causes of hypogonadism in men. It is due to the appearance of a supernumerary X chromosome that causes a reduction in the number of spermatozoa in men’s female breasts, testes, but without stromal cells (Leydig cells ) Atrophy, FSH secretion increased. I see a hospital for 47, xxy / 46, xx. Only 3.1% of the karyotype, the treatment is effective, are as follows. Patient, male, 17 years old. Due to bilateral breast enlargement for 4 years