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采用体外实验及动物实验方法，研究绿茶在正常饮用浓度下对胃癌几种高危因素的干预作用及对胃癌细胞增殖的抑制作用。结果表明：绿茶水能有效消除ＮａＮＯ２，消除率与茶剂量对数呈显著正相关；１％绿茶水对鱼露亚硝酸钠饮水诱导大鼠ＬＰＯ增高有明显阻抑作用；１％绿茶水对鱼露亚硝酸钠饮水诱导的胃粘膜增生肥厚有一定遏制保护作用；１％绿茶水对酒精引起的胃粘膜出血性损伤有明显减轻作用；５％绿茶水再稀释２０～２００倍时对胃癌细胞系ＦＧＣ－８５细胞株的增殖均有抑制作用，抑制率随茶浓度增加而升高，呈现剂量－效应关系。
In vitro experiments and animal experiments were used to study the intervention of green tea at normal drinking concentration on several risk factors of gastric cancer and its inhibitory effect on proliferation of gastric cancer cells. The results showed that green tea water could effectively eliminate NaNO2, and the elimination rate had a significant positive correlation with the logarithm of tea dose; 1% green tea water had a significant inhibitory effect on the increase of LPO in rats induced by drinking water with sodium nitrite; 1% green tea water was used for fish The dehydration and hypertrophy of gastric mucosa induced by drinking water with sodium nitrite had certain protective effect; 1% green tea water had significant effect on alcohol-induced gastric mucosal hemorrhagic injury; 5% green tea water was diluted 20-200 times for gastric cancer cell lines. The proliferation of FGC-85 cell line was inhibited, and the inhibition rate increased with tea concentration, showing a dose-effect relationship.