新生儿红斑狼疮(LE)的临床特征为短暂的 LE 皮损,伴有或无先天性心脏传导阻滞和血液学的异常。新生儿 LE 由 Mc Cuistion 等于1954年首次报道。其报告的一例新生儿在出生时头皮及面部有散在的红斑,直径0.5—3cm,表面有鳞屑,毛囊性角栓和萎缩。头皮损害的组织学检查示角化过度,角质栓,棘层萎缩或增厚,基底细胞层液化变性,真皮血 The clinical features of neonatal lupus erythematosus (LE) are transient LE lesions with or without congenital heart block and hematologic abnormalities. Neonatal LE was first reported by Mc Cuistion in 1954. An example of a newborn reported at birth was a scattered erythema on the scalp and face with a diameter of 0.5-3 cm and scales, follicular acanthosis and atrophy. Histological examination of scalp lesions showed hyperkeratosis, keratinization, stratum spinosum atrophy or thickening, basal cell layer liquefaction degeneration, dermal blood