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目的探讨乌拉地尔在治疗急性左心衰竭中的临床疗效。方法 3 2例急性左心衰竭患者 ,在吸氧、洋地黄、利尿剂的基础上 ,给予乌拉地尔 5 0 mg溶于 2 5 0 ml液体中静脉滴注 ,速度 10 0～ 40 0 μg/ min疗程 1～ 6天。用乌拉地尔的同时未用其他血管扩张剂。结果使用乌拉地尔治疗 3 0～ 60分钟后 ,大部分患者症状、体征、血流动力学指标明显改善 ,显效 14例 ,有效 15例 ,总有效率 90 .7%。治疗后收缩压、舒张压、心率及收缩压与心率乘积均明显降低 ,动脉血氧分压则明显升高 ,均有显著性差异 (P<0 .0 5或 P<0 .0 1)。结论乌拉地尔治疗急性左心衰竭疗效显著 ,是治疗急性左心衰竭的理想药物
Objective To investigate the clinical efficacy of urapidil in the treatment of acute left heart failure. Methods 32 patients with acute left heart failure, on the basis of oxygen inhalation, digitalis and diuretics, were given 0.5 mg of aloe-diuretic dissolved in 250 ml of liquid for intravenous infusion at the speed of 10 0-40 0 μg / min treatment of 1 to 6 days. With urapidil without the use of other vasodilators. Results After 30 to 60 minutes of treatment with Urapidil, the symptoms, signs and hemodynamics of most patients were significantly improved. 14 cases were markedly effective and 15 cases were effective. The total effective rate was 90.7%. After treatment, systolic blood pressure, diastolic blood pressure, heart rate and systolic blood pressure and heart rate product were significantly lower, arterial oxygen pressure was significantly increased, both were significantly different (P <0.05 or P <0.01). Conclusion Urapidil is effective in the treatment of acute left heart failure and is an ideal drug for the treatment of acute left heart failure