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Wegener肉芽肿(WG)是一病因不明,以上下呼吸道肉芽肿性血管炎为特征的一种疾病,并可累及肾脏。报道1例局限于头颈部坏疽性脓皮病样损害的Wegener肉芽肿。 患者男性,24岁,于1986年第一次就诊。前额,左耳基底部有深在性溃疡,开始表现为水疱,否认其他不适。检查:前额有3个1cm~2左右的溃疡,紫色边界,左耳与枕骨间有4cm×6cm大小的溃疡。分泌物作细菌、分支杆菌及真菌培养均(一);皮损病理显示,假性上皮瘤增生伴有表皮和真皮微脓疡,在真皮下部有弥漫性混合性细胞浸润,PAS染色(一)。根据临床和病理,
Wegener’s granulomatosis (WG) is a disease characterized by an unknown cause characterized by upper and lower respiratory tract granulomatous vasculitis and can affect the kidneys. One case of Wegener’s granulomatosis, which is localized to pyoderma gangrenosum-like lesions of the head and neck, was reported. Male patient, 24 years old, first visit in 1986. Forehead, the left ear base deep ulcers in the beginning, manifested as blisters, deny other discomfort. Check: There are three forehead 1cm ~ 2 ulcers, purple border, between the left ear and occipital 4cm × 6cm size ulcer. Secretions as bacteria, mycobacteria and fungal culture are (a); pathological lesions showed pseudoepithelial hyperplasia accompanied by epidermal and dermal micro abscess, diffuse mixed cell infiltration in the dermis, PAS staining (a) . According to clinical and pathological,