长期口服肾上腺皮质类固醇会引起肾上腺抑制。而二丙酸氯地米松则不明显抑制肾上腺。本文报告用双盲对照试验,在中度严重的慢性支气管哮喘中,试用二丙酸氯地米松气雾剂的结果。被试对象为20例门诊哮喘患者。男女各10例。5例(4例用安慰剂,1例用氯地米松)于试验中由于急性呼吸道感染所致病情严重恶化而停药,其他15例完成试验。所有患者均兼发呼吸道阻塞和肺功能异常。其中11例为症状性特应性哮喘(皮试阳性);4 Long-term oral adrenocortical steroids can cause adrenal suppression. While beclomethasone dipropionate did not significantly inhibit the adrenal gland. This article reports the results of a double-blind controlled trial of beclomethasone dipropionate aerosol in moderately severe chronic bronchial asthma. Subjects were 20 outpatients with asthma. 10 men and women in each. Five patients (4 with placebo and 1 with beclomethasone) were discontinued due to a serious deterioration of their condition due to acute respiratory infection in the study. The other 15 patients completed the trial. All patients had concurrent respiratory blockage and pulmonary dysfunction. 11 cases of symptomatic atopic asthma (skin test positive); 4