维生素D缺乏是骨质疏松症以及其他慢性疾病(包括1型糖尿病、高血压、代谢综合征和缺血性心脏病)的危险因素。胆固醇与维生素D均参与7-脱氢胆固醇代谢途径。本研究旨在评价阿托伐他汀对急性缺血性心脏病患者维生素D水平可能产生的影响。共纳入83例急性冠状动脉综合征患者(52例男性和31例女性;75例急性心肌梗死以及8例不稳定型心绞痛)。诊断明确后患者接受阿托伐他汀治疗作为二级预防措施。 Vitamin D deficiency is a risk factor for osteoporosis and other chronic diseases including type 1 diabetes, hypertension, metabolic syndrome and ischemic heart disease. Both cholesterol and vitamin D are involved in the 7-dehydrocholesterol metabolic pathway. This study was designed to evaluate the possible effect of atorvastatin on vitamin D levels in patients with acute ischemic heart disease. A total of 83 patients with acute coronary syndrome (52 males and 31 females; 75 AMI and 8 unstable angina) were enrolled. After diagnosis, patients receive atorvastatin as a secondary preventive measure.