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为解决中药麻醉和针刺麻醉手术中腹肌紧张问题,从中草药中寻找研制肌松剂,浙江医科大学对该省产的华瓜木进行了研究,其总硷和单体消旋毒藜硷(d1—Anabasine)经临床证实有效,但因使用大量昂贵有毒的氯仿和结晶纯化的复杂操作,至今难于投入生产。我们在本省采集的华瓜木Alangiumchinense(Lour)Harms,按有机溶媒常法提取即得单一的有效成分消旋毒藜硷,现用直接水煎酒沈的方法制成合格的单成份针剂“肌松二号”(以下简称“肌二”),提
In order to solve the problems of abdominal muscle tension in traditional Chinese medicine anesthesia and acupuncture anesthesia, looking for the development of muscle relaxants from Chinese herbal medicine, Zhejiang Medical University studied Huaguomu produced in the province, and its total caries and monomer racemic drugs ( d1—Anabasine) has been clinically proven to be effective, but it has been difficult to put into production due to the use of a large amount of expensive and toxic chloroform and complicated purification of crystals. The Chinese herbal medicine Alangiumchinense (Lour) Harms collected in our province was extracted by the organic solvent method to obtain a single active ingredient, racemic toxin, and it is now prepared into a qualified single-component injection using a direct decoction method. Song No. 2 (hereinafter referred to as “Muscle 2”)