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早产是现代产科中遇到的常见问题,虽然目前无特别有效口服药物治疗能改善结局,但静脉给予β-受体激动剂抑制子宫收缩已被广泛运用。博利康尼是一种选择性β_2-肾上腺素能受体激动剂,能抑制子宫平滑肌收缩,但有许多副作用如血糖、血胰岛素和血乳酸水平升高,震颤及心悸。博利康尼可引起空腹和餐后血糖及胰岛素水平升高,然而妊娠期口服博利康尼引起血糖代谢改变的确切机理目前尚不清楚。另外,博利康尼对母儿能量消耗的影响程度也从未有研究报道。
Preterm birth is a common problem encountered in modern obstetrics. Although there is no specific and effective oral drug treatment to improve the outcome, intravenous administration of beta-agonists to uterine contractions has been widely used. Bortrolney is a selective β 2 -adrenoceptor agonist that inhibits uterine smooth muscle contractions but has many side effects such as elevated blood glucose, blood insulin and blood lactate, tremor and palpitations. Boli Kang Ni can cause fasting and postprandial blood glucose and insulin levels, but the exact mechanism of oral administration of boli cinnamic acid during pregnancy induced blood glucose metabolism is unclear. In addition, the effect of boliconi on maternal and child energy consumption has never been reported.