我院2001年6月至2003年11月间,应用美国 AGA 公司的新型 Amplatzer 封堵器(以下简称封堵器)关闭65例室间隔缺损(VSD)。本文通过封堵前心电图表现和封堵后心电图变化,从心电学角度评价 VSD 介入治疗的可行性和安全性。1 资料和方法65例中,男28例,女37例,年龄2～75岁。其中≤14岁50例,体重12～42(平均22.9)kg;≥15岁15例,体重48～82(平均58.6)kg。依据临床体检、X 线胸片、12导联心电图、超声心动图 Our hospital from June 2001 to November 2003, the application of the new American AGA Amplatzer occluder (hereinafter referred to as occluder) to close 65 cases of ventricular septal defect (VSD). This paper evaluates the feasibility and safety of interventional treatment of VSD from the perspective of electrocardiography through the manifestation of the pre-occlusion ECG and the ECG changes after occlusion. 1 Materials and Methods 65 cases, 28 males and 37 females, aged 2 to 75 years. Among them, 50 cases were ≤14 years old, weighing 12 to 42 (mean 22.9) kg; 15 years old ≥ 15 years old and weighing 48 to 82 (average 58.6) kg. According to clinical examination, X-ray, 12-lead ECG, echocardiography