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转移因子(transfer factor,TF)是从有免疫力供体的淋巴细胞抽提物中分离出来的一种低分子量肽-核苷酸复合物。自1949年Lawrence 等发现 TF 以来,国内外对 TF 进行了一系列研究。近几年来,我们参照有关资料,利用手术切除的人脾为原料,用透析法制备 TF,供临床应用,收到了一定的效果,并对其生产工艺进行了初步考察。一、转移因子提取取新鲜或冰冻的去脂肪等结缔组织的脾组织200g,用灭菌生理盐水洗涤,置绞肉机中绞碎,加灭菌生理盐水200ml,再置8000～10000
Transfer factor (TF) is a low-molecular-weight peptide-nucleotide complex isolated from lymphocyte extracts from immune donors. Since Lawrence et al found TF in 1949, a series of researches on TF have been carried out at home and abroad. In recent years, we refer to the relevant data, the use of surgical resection of human spleen as raw material, prepared by dialysis TF, for clinical application, received a certain effect, and its production process were initially investigated. First, the transfer factor extraction Take fresh or frozen to fat and other connective tissue spleen tissue 200g, washed with sterilized saline, home mincer minced, add sterile saline 200ml, and then placed 8000 ~ 10000