丝裂霉素是一种对胃肠道恶性肿瘤有效的抗癌抗生素,但对骨髓具有毒性。丝裂霉素的稳定性很重要,因降解产物会增加毒性、降低药效。本文作者对丝裂霉素在静脉输注液中的稳定性做了实验研究。供试样品分两组,第一组在装有50m15%葡萄糖注射液或0.9%氯化钠注射液的聚氯乙烯小袋中分别将 Mitomycin is a potent anti-cancer antibiotic for gastrointestinal malignancies but is toxic to the bone marrow. The stability of mitomycin is very important, because the degradation products will increase the toxicity and reduce the efficacy. The authors did an experimental study of the stability of mitomycin in intravenous infusion. The test samples were divided into two groups, the first group in a polyvinyl chloride pouch containing 50m15% glucose injection or 0.9% sodium chloride injection were respectively