Iohexol 是一种新的非离子型造影剂,经动物实验和临床应用证明它具有与阿米培克同样的优点,且毒性反应和血脑屏障损害较阿米培克轻。作者把两种造影剂用双盲法进行了60例选择性脑血管造影的比较。结果尽管有大量的造影剂注入颈外动脉和椎动脉,如使用常规造影剂常有疼痛反应,但这两种造影剂在注药期间或随后的24小时内均未出 Iohexol is a new non-ionic contrast agent that has been demonstrated in animal and clinical applications to have the same advantages as amipelocaine with less toxicity and blood-brain barrier damage than ampeptone. The authors compared 60 patients with selective cerebral angiography using two contrast agents by double-blind method. Results Although a large amount of contrast agent was injected into the external carotid artery and the vertebral artery, as is usual with conventional contrast agents, both contrast agents did not show up during or within the next 24 hours