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自从1973年Carlson和Eriksson应用前列腺素E_1(以下简称PGE_1)治疗严重下肢缺血性疾病获得成功以后,应用的指征不断扩大,治疗的病例也日趋增多,为不能施行血管重建手术或血管重建手术失败的病人,又提供了一个新的有效药物。我校研制的PGE_1,已开始用于治疗冠心病。现综述国外PGE_1治疗末梢动脉闭塞性疾病的部分文献,愿为扩大PGE_1的临床应用,提供一些参考资料。
Since 1973, Carlson and Eriksson prostaglandin E_1 (hereinafter referred to as PGE_1) success in the treatment of severe lower extremity ischemic disease, the application of the indications continue to increase, the treatment of cases are also increasing, for not be able to perform revascularization or revascularization Failure of the patient, but also provides a new effective drug. PGE_1 developed by our school has been used to treat coronary heart disease. Now summarize the foreign PGE_1 treatment of peripheral arterial occlusive disease in some literature, is willing to expand the clinical application of PGE_1, to provide some references.