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目的:观察妇产科手术患者术后感染的病原菌分布情况,分析病原菌的耐药性。方法:选取2014年8月至2016年4月在阳春市潭水中心卫生院妇产科接受手术治疗术后发生感染的37例患者作为研究对象,采集其感染部位分泌物进行细菌鉴定和药敏试验,统计病原菌种类,观察药敏试验结果。结果:37例患者感染部位分泌物中共分离出96株病原菌,其中革兰阴性菌所占比例为59.4%,高于革兰阳性菌的38.5%,差异具有统计学意义(P<0.05),真菌所占比例为2.1%,与革兰阴性菌、革兰阳性菌所占比例比较,差异具有统计学意义(P<0.05)。药敏试验结果显示主要革兰阴性菌(铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌)对头孢他啶、头孢唑林、头孢噻肟的耐药率均大于60%,主要革兰阳性菌(金黄色葡萄球菌、粪肠球菌)对青霉素、利福平的耐药率均大于70%。结论:妇产科手术患者术后感染病原菌分布较为广泛,一部分病原菌的耐药性较强,临床应高度重视感染的控制和抗菌药物的合理选择。
Objective: To observe the distribution of pathogens in postoperative infection in obstetrics and gynecology patients and analyze the drug resistance of pathogens. Methods: From August 2014 to April 2016, 37 patients with postoperative infection in obstetrics and gynecology department of Tanchun Water Center Hospital of Yangchun City were selected as the research object. The secretions from the infected sites were collected for bacterial identification and drug susceptibility Test, statistical types of pathogens, drug susceptibility test results observed. Results: A total of 96 strains of pathogens were isolated from the secretions of 37 patients. The proportion of Gram-negative bacteria was 59.4%, higher than that of Gram-positive bacteria (38.5%), the difference was statistically significant (P <0.05) Accounting for 2.1%. The difference was statistically significant compared with the proportion of Gram-negative bacteria and Gram-positive bacteria (P <0.05). Susceptibility test results showed that the major gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae) on ceftazidime, cefazolin, cefotaxime resistance rates were greater than 60%, the main Gram Positive bacteria (Staphylococcus aureus, Enterococcus faecalis) penicillin, rifampin resistance rates were greater than 70%. Conclusion: Obstetrics and Gynecology patients with postoperative infection pathogens more widely distributed, part of the pathogenic bacteria drug resistance is strong, the clinical should attach great importance to infection control and rational choice of antimicrobial agents.