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臀果木提取物可诱导大鼠前列腺组织细胞凋亡。用该提取物处理大鼠，４ｄ，９ｄ和１４ｄ后取前列腺，用ＨＥ染色观察细胞形态变化，ＤＮＡ凝胶电泳和流式细胞术（ＦＣＭ）定性、定量ＤＮＡ的降解及凋亡率。结果前列腺组织出现表皮细胞萎缩；ＤＮＡ琼脂糖凝胶电泳出现“梯形”条带；细胞凋亡率背前叶、背侧叶和腹叶分别为０．６７％，３．４２％和６．４９％（４ｄ），０．３２％，７．２５％和１０．１２％（９ｄ），０．７７％，５．４３％和７．４６％（１４ｄ）。表明臀果木提取物能诱导大鼠前列腺背侧叶和腹叶细胞凋亡。
Pygeum vulgare extract can induce apoptosis of rat prostate tissue. Rats were treated with the extract, prostates were taken after 4d, 9d and 14d, HE staining was used to observe the cell morphological changes, DNA gel electrophoresis and flow cytometry (FCM) qualitative, quantitative DNA degradation and apoptosis rate. Results Atrophy of epidermal cells appeared in prostate tissue; “trapezoidal” band appeared on DNA agarose gel electrophoresis; apoptotic rate was 0.67%, 3.42%, and 6.49 in dorsal, dorsal and ventral leaves, respectively. % (4d), 0.32%, 7.25% and 10.12% (9d), 0.77%, 5.43% and 7.46% (14d). It showed that Pygeum vulgare extract could induce apoptosis of rat dorsal prostate and ventral cells.