Objective: To observe the effect of Xuesaitong (血塞通, XST) soft capsule in interference treatment on patients of nephrosis syndrome (NS) during corticosteroid (CS) dose reducing stage. Methods: Seventy-one NS patients applying prednisone and initiating dose reducing stage were randomized into trial group and control group. On the basis of conventional prednisone dose reduction of both groups, the trial group was given additionally XST, and the treatment course ended with the reduction to maintenance dose. In the course of observation, those who did not comply with the criteria of observation were excluded. Before and after the dose reduction, TCM syndrome scoring, 24 hrs urinary protein amount, blood β2-microglobulin (β2-MG), urinary β2-MG, blood fibrinogen (Fbg), plasma prothrombin time (PT), blood lipid, etc. were observed. Results: The trial group of XST could obviously lower their urinary protein amount and blood lipid level (P<0.05 or P<0.01), markedly improve the blood coagulation parameters ( Objective: To observe the effect of Xuesaitong (Xuesetong, XST) soft capsule in interference treatment on patients of nephrosis syndrome (NS) during corticosteroid (CS) dose reducing stage. Methods: Seventy-one NS patients applying prednisone and initiating patient reducing Stage were randomized into trial group and control group. On the basis of conventional prednisone drug reduction of both groups, the trial group was given additional xST, and the treatment course ended with the reduction to maintenance dose. In the course of observation, those who Did not comply with the criteria of observation were excluded. Before and after the patient reduction, TCM syndrome scoring, 24 hrs urinary protein amount, blood β2-microglobulin (β2-MG), urinary β2-MG, blood fibrinogen (Fbg), plasma Prothrombin time (PT), blood lipid, etc. were observed. Results: The trial group of XST could apparent lower urinary protein amount and blood lipid level (P<0.05 or P<0.01), markedly improving the blood co Agulation parameters (