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目的:探讨重组人干扰素α-1b联合3%氯化钠注射液雾化吸入治疗婴幼儿支气管肺炎(喘息型)的临床疗效.方法:随机选取2015年1月至12月在我院就诊的60例小儿支气管肺炎(喘息型)患儿作为本次研究对象,按治疗方案不同分为常规雾化组(30例)和联合雾化组(30例),常规雾化组行3%氯化钠注射液雾化吸入治疗,联合雾化组行重组人干扰素α-1b联合3%氯化钠注射液雾化吸入治疗,比较两组患儿治疗效果、临床症状缓解时间及住院时间.结果:联合雾化组治疗总有效率高于常规雾化组(90.00%vs.76.67%),但差异无统计学意义(P>0.05);联合雾化组喘息、咳嗽、喘鸣音、肺部湿啰音等症状缓解时间及住院时间较常规雾化组短,差异统计学意义(P0.05).The time of symptom such as breathe,cough,wheezing rales and moist crackles disappearance and hospitalization time of joint atomized group were obviously shorter than those of routine atomized group,with statistical significance(p<0.05).Conclusions:The α-interferon combined with 3% sodium chloride solution for aerosol inhalation in nurseling with asthmatic pneumoniahas promising clinical effect,which can effectively improve clinical manifestations of nurseling and shorten hospital stay.