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目的 :观察小剂量氨茶碱、必可酮伍用治疗咳嗽变异型哮喘的疗效及安全性。方法 :36例咳嗽变异型哮喘患者均停用所有抗菌素及其它止咳祛痰药物 ,口服氨茶碱 5 0 mg,每日三次 ,同时吸入必可酮 10 0 μg,每日三次 (吸入后嗽口 )。结果 :36例患者于治疗后 7d~ 10 d咳嗽消失 ,治疗后第 30 d复查气道反应性降至正常。结论 :小剂量氨茶碱、必可酮伍用治疗咳嗽变异型哮喘疗效显著而又安全可靠 ,值得推广应用
Objective: To observe the efficacy and safety of low-dose aminophylline and bixodone in treating cough variant asthma. Methods: Thirty-six patients with cough variant asthma were discontinued of all antibiotics and other cough expectorant drugs. Oral aminophylline 50 mg orally three times a day, while inhaling ketoconazole 100 μg three times a day (after inhalation, ). RESULTS: Thirty-six patients disappeared on day 7 and 10 after treatment. The airway reactivity dropped to normal on the 30th day after treatment. Conclusion: Aminophylline and bixodone are effective and safe in treatment of cough variant asthma, which is worthy of popularization and application