近日,来自赫特福德大学的研究人员通过研究揭示了关键性致癌基因调节肿瘤细胞信号的特殊机制,相关研究刊登于国际杂志Cell上。实体癌症是一种包含肿瘤细胞和基质细胞的异型细胞系统,肿瘤细胞癌基因对基质细胞的抑制会明显影响癌症生物学的机制,而且异常的肿瘤基质信号会调节许多癌症的标志;当单一的肿瘤机制信号的癌基因驱动调节子被鉴别时,目前研究人员并不清楚通过整个异型细胞系统的 Recently, researchers from the University of Hertfordshire revealed some specific mechanisms by which key oncogenes can modulate tumor cell signaling, a study published in the international journal Cell. Solid cancer is a heterogeneous cellular system that contains tumor cells and stromal cells. The inhibition of stromal cells by tumor cell oncogenes significantly affects the mechanism of cancer biology, and aberrant tumor stroma signals regulate many markers of cancer. When a single When oncogene-driven regulators of tumor signaling are identified, the current researchers are not clear about the entire