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精神药物最初使用于临床三年之后,即有人首先报导药物引起谵妄状态,随着新的精神药物的应用,关于此种并发症的报告逐渐增多。至今根据多数学者材料,并发率约占1～3%。多见于用药的前6周,亦可见于较长的时间用药之后在药量剧增、更换药物、或停药之时。在并发病的发生率中,药物剂量的变动较药物的绝对剂量的影响尤著。谵妄在抗忧郁剂治疗中比精神安定剂治疗中常见,多种药物综合治疗或加矫正剂时(指抗震颤麻痹征药物等—译者)并发率显著增高。
Psychiatry was first used clinically for three years, when someone first reported the state of delirium caused by the drug. With the introduction of new psychoactive drugs, reports of such complications have been increasing. According to most scholars so far, the incidence rate of about 1 to 3%. More common in the first 6 weeks of medication, can also be seen after a longer period of time after the drug dosage increase, the replacement of drugs, or withdrawal time. In the incidence of concurrent disease, the drug dose changes more particularly than the absolute dose of the drug. Delirium is more common in the treatment of antidepressants than in neuroleptic agents, with a significant increase in the concurrent rates of multiple medications or orthodontics (referring to anti-paralytic drugs, etc.).