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目的：分析中枢神经系统（ｃｅｎｔｒａｌ ｎｅｒｖｏｕｓ ｓｙｓｔｅｍ，ＣＮＳ）新型隐球菌感染临床特征。方法：对 ６０例患者进行临床分析。结果：患者脑脊液呈无色浑浊、白细胞升高、其中以淋巴细胞和单核细胞为主。蛋白质升高、葡葡糖和氯化物减低，墨汁染色及苏木素－伊红染色均可发现新型隐球菌。几乎所有的患者有头痛、９０％有发热、７３％有呕吐、６５％有不同程度的意识障碍和偏瘫、约半数还有听力减退、双目失明和抽搐。结论：脑脊液墨汁或苏木素－伊红染色检查有助于鉴别。
Objective: To analyze the clinical features of cryptococcal neoformans infection in the central nervous system (CNS). Methods: Sixty patients underwent clinical analysis. Results: The cerebrospinal fluid was colorless and turbid, white blood cells increased, with lymphocytes and monocytes predominate. Increased protein, reduced glucose and chloride, ink stain and hematoxylin-eosin staining can be found in Cryptococcus neoformans. Almost all patients had headache, 90% had fever, 73% had vomiting, 65% had varying degrees of disturbance of consciousness and hemiparesis, and about half had hearing loss, blindness and convulsions. CONCLUSIONS: Cerebrospinal fluid ink or hematoxylin-eosin staining can be used to identify.